The UK professional body guidelines recommend that sperm, egg and embryo donors should be screened for CMV antibodies. This will show if they have been infected with CMV before or currently have an active infection. People found to have an active infection are recommended to defer donation. Advice from your fertility clinic should always be sought.
The risk of transmission of CMV through egg or embryo donation is negligible, therefore fertility centres may consider the use of eggs or embryos from CMV-positive donors (that is those individuals who have had CMV before) for women who are CMV-negative.
CMV can be found in semen, therefore it is generally recommended that CMV-negative women (those individuals who have never had CMV before) are matched with donor sperm samples from CMV-negative donors. In general, women who are CMV-positive may received donor sperm from men who have had CMV before.
As the evidence is not clear cut, and practice can vary, the recommendation about whether to use a CMV positive donor should be a matter of clinical and personal judgement and should be discussed with staff at your fertility clinic.
Whether donor samples are received from CMV-positive or CMV-negative individuals, CMV can still be caught during pregnancy and therefore all pregnant women are advised to follow risk reduction measures.